Papers in 2000
Nitta K, Kikawada E, Uchida K, Honda K, Kawashima A, Yumura W, Nihei H.
Plasma levels of the mature form of adrenomedullin and disease activity in patients with IgA nephropathy.
Nephron. 2000 Dec;86(4):520-1. No abstract available.
Hoeldtke NJ, Wagner RK, Calhoun BC, Hume RF Jr.
Vasodilatory response of fetoplacental vasculature to adrenomedullin after constriction with the thromboxane sympathomimetic U46619.
Am J Obstet Gynecol. 2000 Dec;183(6):1573-1578.
Buhlmann N, Aldecoa A, Leuthauser K, Gujer R, Muff R, Fischer JA, Born W.
Glycosylation of the calcitonin receptor-like receptor at Asn(60) or Asn(112) is important for cell surface expression.
FEBS Lett. 2000 Dec 15;486(3):320-324.
Pio R, Martinez A, Unsworth EJ, Kowalak JA, Bengoechea JA, Zipfel PF, Elsasser TH, Cuttitta F.
Complement factor H is a serum binding protein for adrenomedullin. The resulting complex modulates the bioactivities of both partners.
J Biol Chem. 2000 Dec 14
Dobrzynski E, Wang C, Chao J, Chao L.
Adrenomedullin Gene Delivery Attenuates Hypertension, Cardiac Remodeling, and Renal Injury in Deoxycorticosterone Acetate-Salt Hypertensive Rats.
Hypertension. 2000 Dec;36(6):995-1001.
Fujioka M, Nishio K, Sakaki T, Minamino N, Kitamura K.
Adrenomedullin in patients with cerebral vasospasm after aneurysmal subarachnoid hemorrhage.
Stroke. 2000 Dec;31(12):3079-83. No abstract available.
Totsune K, Takahashi K, Mackenzie HS, Murakami O, Arihara Z, Sone M, Mouri T, Brenner BM, Ito S.
Increased gene expression of adrenomedullin and adrenomedullin-receptor complexes, receptor-activity modifying protein (RAMP)2 and calcitonin-receptor-like receptor (CRLR) in the hearts of rats with congestive heart failure.
Clin Sci (Colch). 2000 Dec 1;99(6):541-546.
Yamakawa H, Imamura T, Matsuo T, Onitsuka H, Tsumori Y, Kato J, Kitamura K, Koiwaya Y, Eto T.
Diastolic wall stress and ANG II in cardiac hypertrophy and gene expression induced by volume overload.
Am J Physiol Heart Circ Physiol. 2000 Dec;279(6):H2939-H2946.
Nagaya N, Nishikimi T, Uematsu M, Satoh T, Oya H, Kyotani S, Sakamaki F, Ueno K, Nakanishi N, Miyatake K, Kangawa K.
Haemodynamic and hormonal effects of adrenomedullin in patients with pulmonary hypertension.
Heart. 2000 Dec;84(6):653-658.
Vijay P. Related Articles
Adrenomedullin in the treatment of pulmonary hypertension.
Heart. 2000 Dec;84(6):575-576. No abstract available.
Terata K, Miura H, Liu Y, Loberiza F, Gutterman DD. Related Articles
Human coronary arteriolar dilation to adrenomedullin: role of nitric oxide and K(+) channels.
Am J Physiol Heart Circ Physiol. 2000 Dec;279(6):H2620-H2626.
Del Bene R, Lazzeri C, Barletta G, Vecchiarino S, Guerra CT, Franchi F, La Villa G.
Effects of low-dose adrenomedullin on cardiac function and systemic haemodynamics in man.
Clin Physiol. 2000 Nov;20(6):457-65.
Apodaca CC, Moore KH, Rossignol TM, Pierce B, Matej LA, Hume RF Jr, Calhoun BC.
Localization of messenger ribonucleic acid for adrenomedullin and adrenomedullin receptor in the human placenta in normal pregnancies and pregnancies complicated by oligohydramnios.
Am J Obstet Gynecol. 2000 Nov;183(5):1213-1219.
Kinoshita H, Fujimoto S, Kitamura K, Matsuura Y, Uezono S, Hisanaga
S, Eto T.
Increased plasma levels of mature adrenomedullin in chronic glomerulonephritis.
Nephron. 2000 Nov;86(3):333-8.
Balat A, Cekmen M, Yurekli M, Gulcan H, Kutlu O, Turkoz Y, Yologlu S.
Adrenomedullin and nitrite levels in children with minimal change nephrotic syndrome.
Pediatr Nephrol. 2000 Nov;15(1-2):70-3.
Sams A, Knyihar-Csillik E, Engberg J, Szok D, Tajti J, Bodi I, Edvinsson L, Vecsei L, Jansen-Olesen I.
CGRP and adrenomedullin receptor populations in human cerebral arteries: in vitro pharmacological and molecular investigations in different artery sizes.
Eur J Pharmacol. 2000 Nov 17;408(2):183-193.
Takahashi K, Yoshinoya A, Murakami O, Totsune K, Shibahara S. Related Articles
Secretion of endothelin-1 and adrenomedullin by SW-13 human adrenocortical carcinoma cells.
J Cardiovasc Pharmacol. 2000 Nov;36(5 Suppl 1):S393-4.
Hashimoto H, Akimoto M, Maeda A, Shigemoto M, Yamashita K, Yokoyama I.
Changes in vasoactive substances during gastric ulcer healing.
J Cardiovasc Pharmacol. 2000 Nov;36(5 Suppl 1):S278-81.
Stangl V, Dschietzig T, Bramlage P, Boye P, Kinkel H, Staudt A, Baumann G, Felix SB, Stangl K.
Adrenomedullin and myocardial contractility in the rat.
Eur J Pharmacol. 2000 Nov 10;408(1):83-89.
Parameswaran N, Aiyar N, Wu H, Brooks DP, Nambi P, Spielman WS.
Desensitization and resensitization of
adrenomedullin-sensitive receptor in rat mesangial cells.
Eur J Pharmacol. 2000 Nov 3;407(3):205-210.
Kitamuro T, Takahashi K, Nakayama M, Murakami O, Hida W, Shirato
K, Shibahara S.
Induction of adrenomedullin during hypoxia in cultured human glioblastoma cells.
J Neurochem. 2000 Nov;75(5):1826-33.
Ozbek E, Yurekli M, Soylu A, Davarci M, Balbay MD.
The role of adrenomedullin in varicocele and impotence.
BJU Int. 2000 Oct;86(6):694-8.
Troughton RW, Lewis LK, Yandle TG, Richards AM, Nicholls MG.
Hemodynamic, hormone, and urinary effects of adrenomedullin infusion in essential hypertension.
Hypertension. 2000 Oct;36(4):588-93.
Charles CJ, Rademaker MT, Richards AM, Cooper GJ, Coy DH, Nicholls MG.
Adrenomedullin attenuates pressor response to angiotensin II in conscious sheep.
J Cardiovasc Pharmacol. 2000 Oct;36(4):526-32.
Nishikimi T, Kangawa K.
[Behavior and pathophysiological significance of adrenomedullin in essential hypertension].
Nippon Rinsho. 2000 Jan;58 Suppl 1:481-6. Japanese. No abstract available.
Kitamura K, Eto T.
[Adrenomedullin and related peptides].
Nippon Rinsho. 2000 Jan;58 Suppl 1:121-5. Japanese. No abstract available.
Kuriyama S, Kobayashi H, Tomonari H, Tokudome G, Hayashi F, Kaguchi Y, Horiguchi M, Ishikawa M, Hosoya T.
Circulating adrenomedullin in erythrocopietin-induced hypertension.
Hypertens Res. 2000 Sep;23(5):427-32.
Hata K, Takebayashi Y, Akiba S, Fujiwaki R, Iida K, Nakayama K, Nakayama S, Fukumoto M, Miyazaki K.
Expression of the adrenomedullin gene in epithelial ovarian cancer.
Mol Hum Reprod. 2000 Oct;6(10):867-872.
Dotsch J, Harmjanz A, Christiansen H, Hanze J, Lampert F, Rascher W.
Gene expression of neuronal nitric oxide synthase and adrenomedullin in human neuroblastoma using real-time PCR.
Int J Cancer. 2000 Oct 15;88(2):172-175.
Hugghins SY, Champion HC, Cheng G, Kadowitz PJ, Jeter JR Jr.
Vasorelaxant responses to endomorphins, nociceptin, albuterol, and adrenomedullin in isolated rat aorta.
Life Sci. 2000 Jun 16;67(4):471-6.
Kobayashi H, Minami S, Yamamoto R, Masumoto K, Yanagita T, Uezono Y, Tsuchiya K, Mohri M, Kitamura K, Eto T, Wada A.
Adrenomedullin receptors in rat cerebral microvessels.
Brain Res Mol Brain Res. 2000 Sep 30;81(1-2):1-6.
Lainchbury JG, Meyer DM, Jougasaki M, Burnett JC Jr, Redfield MM.
Effects of adrenomedullin on load and myocardial performance in normal and heart-failure dogs.
Am J Physiol Heart Circ Physiol. 2000 Sep;279(3):H1000-6.
Ali N, Yousufzai SY, Abdel-Latif AA.
Activation of particulate guanylate cyclase by adrenomedullin in cultured SV-40 transformed cat iris sphincter smooth muscle (SV-CISM-2) cells.
Cell Signal. 2000 Jul 1;12(7):491-498.
Clementi G, Floriddia ML, Prato A, Marino A, Drago F.
Adrenomedullin and ocular inflammation in the rabbit.
Eur J Pharmacol. 2000 Jul 21;400(2-3):321-326.
Wu D, Eberlein W, Rudolf K, Engel W, Hallermayer G, Doods H.
Characterisation of calcitonin gene-related peptide receptors in rat atrium and vas deferens: evidence for a [Cys(Et)(2,7)]hCGRP-preferring receptor.
Eur J Pharmacol. 2000 Jul 21;400(2-3):313-319.
Zhang JJ, Yoshida H, Chao L, Chao J.
Human adrenomedullin gene delivery protects against cardiac hypertrophy, fibrosis, and renal damage in hypertensive dahl salt-sensitive rats.
Hum Gene Ther. 2000 Sep 1;11(13):1817-27.
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Nishikimi T, Matsuoka H, Shimada K, Matsuo H, Kangawa K.
Production and clearance sites of two molecular forms of adrenomedullin in human plasma.
Am J Hypertens. 2000 Sep;13(9):1032-4.
Troughton RD, Lainchbury JG, McGregor DO, Richards AM, Nicholls MG.
Adrenomedullin in Hypertension.
Curr Hypertens Rep. 2000 Feb;2(1):1-2. No abstract available.
Ladoux A, Frelin C.
Coordinated up-regulation by hypoxia of adrenomedullin and one of its putative receptor (RDC-1) in cells of the rat blood brain barrier.
J Biol Chem. 2000 Sep 8 [epub ahead of print]
Okumura M, Kai H, Arimori K, Iwakiri T, Hidaka M, Shiramoto S, Isohama Y, Miyata T.
Adrenomedullin increases phosphatidylcholine secretion in rat type II pneumocytes.
Eur J Pharmacol. 2000 Sep 8;403(3):189-194.
Kusaka I, Ishikawa S, Fujita N, Higashiyama M, Honda K, Okada K, Saito T.
Inhibition by adrenomedullin of arginine vasopressin-activated mitogen-activated protein kinase in rat glomerular mesangial cells via cAMP production.
Hypertens Res. 1996 Jun;19(2):113-9.
Nishikimi T, Matsuoka H, Ishikawa K, Yoshihara F, Kawano Y, Kitamura K, Saito Y, Kangawa K, Matsuo H, Omae T.
Antihypertensive therapy reduces increased plasma levels of adrenomedullin and brain natriuretic peptide concomitant with regression of left ventricular hypertrophy in a patient with malignant hypertension.
Hypertens Res. 1996 Jun;19(2):97-101.
Ventura S, Lau WA, Buljubasich S, Pennefather JN.
Calcitonin gene-related peptide (CGRP) inhibits contractions of the prostatic stroma of the rat but not the guinea-pig.
Regul Pept. 2000 Jul 28;91(1-3):63-73.
Montuenga LM, Burrell MA, Garayoa M, Llopiz D, Vos M, Moody T, Garcia-Ros D, Martinez A, Villaro AC, Elsasser T, Cuttitta F.
Expression of proadrenomedullin derived peptides in the mammalian pituitary: co-localization of follicle stimulating hormone and proadrenomedullin N-20 terminal peptide-like peptide in the same secretory granules of the gonadotropes.
J Neuroendocrinol. 2000 Jul;12(7):607-17.
Nikitenko LL, MacKenzie IZ, Rees MC, Bicknell R.
Adrenomedullin is an autocrine regulator of endothelial growth in human endometrium.
Mol Hum Reprod. 2000 Sep;6(9):811-819.
Yanagita T, Yamamoto R, Sugano T, Kobayashi H, Uezono Y, Yokoo H, Shiraishi S, Minami Si, Wada A.
Adrenomedullin inhibits spontaneous and bradykinin-induced but not oxytocin- or prostaglandin F(2alpha)-induced periodic contraction of rat uterus.
Br J Pharmacol. 2000 Aug 8;130(8):1727-1730.
Piquard F, Charloux A, Mettauer B, Epailly E, Lonsdorfer E, Popescu S, Lonsdorfer J, Geny B.
Exercise-induced increase in circulating adrenomedullin is related to mean blood pressure in heart transplant recipients.
J Clin Endocrinol Metab. 2000 Aug;85(8):2828-31.
Clausen T.
Effects of amylin and other peptide hormones on Na+-K+ transport and contractility in rat skeletal muscle.
J Physiol. 2000 Aug 15;527(Pt 1):121-130.
Ashton D, Hieble P, Gout B, Aiyar N.
Vasodilatory Effect of Adrenomedullin in Mouse Aorta.
Pharmacology. 2000 Aug;61(2):101-105.
Nitta K, Kawashima A, Oba T, Kikawada E, Narusawa K, Mimuro T, Kabaya T, Nihei H.
Increased plasma levels of adrenomedullin in patients with hemodialysis.
Nephron. 2000 Aug;85(4):360-2. No abstract available.
Dunzendorfer S, Meierhofer C, Xu Q, Wiedermann CJ.
Pentoxifylline-augmented antiproliferative effects of adrenomedullin on vascular smooth muscle cells.
Eur J Heart Fail. 2000 Sep 1;2(3):257-260. No abstract available.
Kinnunen P, Szokodi I, Nicholls MG, Ruskoaho H.
Impact of NO on ET-1- and AM-induced inotropic responses: potentiation by combined administration.
Am J Physiol Regul Integr Comp Physiol. 2000 Aug;279(2):R569-R575.
Petrie MC, McClure SJ, Love MP, McMurray JJ.
Novel neuropeptides in the pathophysiology of heart failure: adrenomedullin and endothelin-1.
Eur J Heart Fail. 1999 Mar;1(1):25-9.
Shan J, Krukoff TL.
Area Postrema Ablation Attenuates Activation of Neurones in the Paraventricular Nucleus in Response to Systemic Adrenomedullin.
J Neuroendocrinol. 2000 Aug;12(8):802-810.
Chu DQ, Choy M, Foster P, Cao T, Brain SD.
A comparative study of the ability of calcitonin gene-related peptide and adrenomedullin(13 - 52) to modulate microvascular but not thermal hyperalgesia responses.
Br J Pharmacol. 2000 Aug 7;130(7):1589-1596.
Salemi R, McDougall JG, Hardy KJ, Wintour EM.
Effect of adrenomedullin infusion on basal and stimulated aldosterone secretion in conscious sheep with cervical adrenal autotransplants.
J Endocrinol. 2000 Aug;166(2):389-399.
Hague S, Zhang L, Oehler MK, Manek S, MacKenzie IZ, Bicknell R, Rees MC.
Expression of the hypoxically regulated angiogenic factor adrenomedullin correlates with uterine leiomyoma vascular density.
Clin Cancer Res. 2000 Jul;6(7):2808-14.
Cheung BM, Lau C, Leung RY, Tong KK, Kumana CR.
Plasma adrenomedullin level in systemic lupus erythematosus.
Rheumatology (Oxford). 2000 Jul;39(7):804-805. No abstract available.
Hirano S, Imamura T, Matsuo T, Ishiyama Y, Kato J, Kitamura K, Koiwaya Y, Eto T.
Differential responses of circulating and tissue adrenomedullin and gene expression to volume overload.
J Card Fail. 2000 Jun;6(2):120-9.
Sata M, Kakoki M, Nagata D, Nishimatsu H, Suzuki E, Aoyagi T, Sugiura S, Kojima H, Nagano T, Kangawa K, Matsuo H, Omata M, Nagai R, Hirata Y.
Adrenomedullin and nitric oxide inhibit human endothelial cell apoptosis via a cyclic GMP-independent mechanism.
Hypertension. 2000 Jul;36(1):83-8.
Evans BM, Rosenblatt MI, Mnayer LO, Oliver KR, Dickerson IM. Related Articles
CGRP-RCP: A novel protein required for signal transduction at CGRP and adrenomedullin receptors.
J Biol Chem. 2000 Jul 19
Pousset F, Masson F, Chavirovskaia O, Isnard R, Carayon A, Golmard JL, Lechat P, Thomas D, Komajda M. Related Articles
Plasma adrenomedullin, a new independent predictor of prognosis in patients with chronic heart failure.
Eur Heart J. 2000 Jun;21(12):1009-14.
Clementi G, Floriddia ML, Prato A, Marino A, Drago F.
Adrenomedullin and ocular inflammation in the rabbit.
Eur J Pharmacol. 2000 Jul 21;400(2-3):321-326.
Wu D, Eberlein W, Rudolf K, Engel W, Hallermayer G, Doods H.
Characterisation of calcitonin gene-related peptide receptors in rat atrium and vas deferens: evidence for a [Cys(Et)(2,7)]hCGRP-preferring receptor.
Eur J Pharmacol. 2000 Jul 21;400(2-3):313-319.
Abe K, Minegishi T, Ibuki Y, Kojima M, Kangawa K.
Expression of adrenomedullin in the human corpus luteum.
Fertil Steril. 2000 Jul 1;74(1):141-145.
Kanenishi K, Kuwabara H, Ueno M, Sakamoto H, Hata T.
Immunohistochemical adrenomedullin expression is decreased in the placenta from pregnancies with pre-eclampsia.
Pathol Int. 2000 Jul;50(7):536-540.
Nanke Y, Kotake S, Shimamoto K, Hara M, Kamatani N.
Raised plasma adrenomedullin patients with systemic sclerosis complicated by pulmonary hypertension.
Ann Rheum Dis. 2000 Jun;59(6):493-4. No abstract available.
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Kuwasako K, Shimekake Y, Masuda M, Nakahara K, Yoshida T, Kitaura M, Kitamura K, Eto T, Sakata T.
Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling.
J Biol Chem. 2000 Jul 5 [epub ahead of print]
Esfandyari T, Macnaughton WK, Quirion R, St Pierre S, Junien JL, Sharkey KA.
A novel receptor for calcitonin gene-related peptide (CGRP) mediates secretion in the rat colon: implications for secretory function in colitis.
FASEB J. 2000 Jul;14(10):1439-1446.
Leclerc M, Brunette MG.
The paradoxical effect of adrenomedullin on Na+ transport by the renal distal tubule luminal membrane.
Mol Cell Endocrinol. 2000 Jun;164(1-2):159-67.
Letizia C, Di Iorio R, De Toma G, Marinoni E, Cerci S, Celi M, Subioli S, D'Erasmo E.
Circulating adrenomedullin is increased in patients with corticotropin-dependent Cushing's syndrome due to pituitary adenoma.
Metabolism. 2000 Jun;49(6):760-3.
Ohinata K, Inui A, Asakawa A, Wada K, Wada E, Yoshikawa M.
Proadrenomedullin N-terminal 20 peptide (PAMP) elevates blood glucose levels via bombesin receptor in mice.
FEBS Lett. 2000 May 12;473(2):207-11.
Kinoshita H, Kato K, Kuroki M, Nakamura S, Kitamura K, Hisanaga S, Fujimoto S, Eto T.
Plasma adrenomedullin levels in patients with diabetes.
Diabetes Care. 2000 Feb;23(2):253-4.
Kubo A, Nishitani Y, Minamino N, Kikumoto K, Kurioka H, Nishino T, Iwano M, Shiiki H, Kangawa K, Dohi K.
Adrenomedullin Gene Transcription Is Decreased in Peripheral Blood Mononuclear Cells of Patients with IgA Nephropathy.
Nephron. 2000 Jul;85(3):201-206.
Oya H, Nagaya N, Furuichi S, Nishikimi T, Ueno K, Nakanishi N, Yamagishi M, Kangawa K, Miyatake K.
Comparison of intravenous adrenomedullin with atrial natriuretic peptide in patients with congestive heart failure.
Am J Cardiol. 2000 Jul 1;86(1):94-98.
Hojo Y, Ikeda U, Katsuki TA, Shimada K. Related Articles
Decreased adrenomedullin production in the coronary circulation of patients with coronary artery disease.
Heart. 2000 Jul;84(1):88.
Gulberg V, Liss I, Gerbes AL.
Determination of plasma adrenomedullin concentrations with commercial radioimmunoassay kits: a note of caution.
Liver Transpl. 2000 May;6(3):384-5. No abstract available.
Tsuruda T, Kato J, Kitamura K, Imamura T, Koiwaya Y, Kangawa K, Komuro I, Yazaki Y, Eto T.
Enhanced Adrenomedullin Production by Mechanical Stretching in Cultured Rat Cardiomyocytes.
Hypertension. 2000 Jun;35(6):1210-1214.
Laoag-Fernandez JB, Otani T, Maruo T.
Adrenomedullin expression in the human endometrium.
Endocrine. 2000 Feb;12(1):15-9.
Husmann K, Sexton PM, Fischer JA, Born W.
Mouse receptor-activity-modifying proteins 1, -2 and -3: amino acid sequence, expression and function.
Mol Cell Endocrinol. 2000 Apr 25;162(1-2):35-43.
Udono T, Takahashi K, Nakayama M, Murakami O, Durlu YK, Tamai M, Shibahara S.
Adrenomedullin in cultured human retinal pigment epithelial cells.
Invest Ophthalmol Vis Sci. 2000 Jun;41(7):1962-70.
Saetrum Opgaard O, Hasbak P, de Vries R, Saxena PR, Edvinsson L.
Positive inotropy mediated via CGRP receptors in isolated human myocardial trabeculae.
Eur J Pharmacol. 2000 Jun 2;397(2-3):373-382.
Montuenga LM, Burrell MA, Garayoa M, Llopiz D, Vos M, Moody T, Garcia-Ros D, Martinez A, Villaro AC, Elsasser T, Cuttitta F.
Expression of Proadrenomedullin Derived Peptides in the Mammalian Pituitary: Co-Localization of Follicle Stimulating Hormone and Proadrenomedullin N-20 Terminal Peptide-Like Peptide in the Same Secretory Granules of the Gonadotropes.
J Neuroendocrinol. 2000 Jul;12(7):607-617.
Nakayama M, Takahashi K, Kitamuro T, Murakami O, Shirato K, Shibahara S.
Transcriptional control of adrenomedullin induction by phorbol ester in human monocytic leukemia cells.
Eur J Biochem. 2000 Jun 15;267(12):3559-3566.
Garayoa M, Martinez A, Lee S, Pio R, An WG, Neckers L, Trepel J, Montuenga LM, Ryan H, Johnson R, Gassmann M, Cuttitta F.
Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis.
Mol Endocrinol. 2000 Jun;14(6):848-62.
Turk HM, Buyukberber S, Sevinc A, Ak G, Ates M, Sari R, Savli H, Cigli A.
Relationship between plasma adrenomedullin levels and metabolic control, risk factors, and diabetic microangiopathy in patients with type 2 diabetes.
Diabetes Care. 2000 Jun;23(6):864-7. No abstract available.
Ornan DA, Chaudry IH, Wang P.
The dissociation between upregulated endothelins and hemodynamic responses during polymicrobial sepsis.
Biochim Biophys Acta. 2000 Jun 15;1501(2-3):211-218.
Manau D, Balasch J, Jimenez W, Fabregues F, Civico S, Casamitjana R, Creus M, Vanrell JA.
Follicular fluid concentrations of adrenomedullin, vascular endothelial growth factor and nitric oxide in IVF cycles: relationship to ovarian response.
Hum Reprod. 2000 Jun;15(6):1295-1299.
Andreis PG, Markowska A, Champion HC, Mazzocchi G, Malendowicz LK, Nussdorfer GG.
Adrenomedullin enhances cell proliferation and deoxyribonucleic acid synthesis in rat adrenal zona glomerulosa: receptor subtype involved and signaling mechanism.
Endocrinology. 2000 Jun;141(6):2098-104.
Parlapiano C, Paoletti V, Campana E, Labbadia G, Giovanniello T, Califano F, Pantone P, Clemente G, Donnarumma L, Musca A.
Adrenomedullin assay and its clinical significance.
Eur Rev Med Pharmacol Sci. 1999 Mar-Apr;3(2):53-61.
Chun TH, Itoh H, Saito T, Yamahara K, Doi K, Mori Y, Ogawa Y, Yamashita J, Tanaka T, Inoue M, Masatsugu K, Sawada N, Fukunaga Y, Nakao K.
Oxidative stress augments secretion of endothelium-derived relaxing peptides, C-type natriuretic peptide and adrenomedullin.
J Hypertens. 2000 May;18(5):575-80.
Kobayashi K, Kubota T, Aso T, Hirata Y, Imai T, Marumo F.
Immunoreactive adrenomedullin (AM) concentration in maternal plasma during human pregnancy and AM expression in placenta.
Eur J Endocrinol. 2000 Jun;142(6):683-687.
Moriyama T, Otani T, Maruo T.
Expression of adrenomedullin by human granulosa lutein cells and its effect on progesterone production.
Eur J Endocrinol. 2000 Jun;142(6):671-676.
Szekely L, Vijay P, Sharp TG, Bando K, Brown JW. Related Articles
Correlation of Plasma Adrenomedullin to Myocardial Preservation During Open-Heart Surgery.
Pediatr Cardiol. 2000 May;21(3):228-233.
Koo DJ, Yoo P, Cioffi WG, Bland KI, Chaudry IH, Wang P. Related Articles
Mechanism of the Beneficial Effects of Pentoxifylline during Sepsis: Maintenance of Adrenomedullin Responsiveness and Downregulation of Proinflammatory Cytokines.
J Surg Res. 2000 Jun 1;91(1):70-76.
Shindo T, Kurihara H, Maemura K, Kurihara Y, Kuwaki T, Izumida T, Minamino N, Ju KH, Morita H, Oh-Hashi Y, Kumada M, Kangawa K, Nagai R, Yazaki Y.
Hypotension and Resistance to Lipopolysaccharide-Induced Shock in Transgenic Mice Overexpressing Adrenomedullin in Their Vasculature.
Circulation. 2000 May 16;101(19):2309-2316.
Ueta Y, Serino R, Shibuya I, Kitamura K, Kangawa K, Russell JA, Yamashita H.
A physiological role for adrenomedullin in rats; a potent hypotensive peptide in the hypothalamo-neurohypophysial system.
Exp Physiol. 2000 Mar;85 Spec No:163S-169S.
Albertin G, Malendowicz LK, Tortorella C, Mazzocchi G, Nussdorfer GG.
Evidence for a paracrine role of adrenomedullin in the physiological resetting of aldosterone secretion by rat adrenal zona glomerulosa.
Peptides. 2000 Mar 1;21(3):413-417.
Demetriou D, Wenter C, Watschinger B.
Vasoactive substances in renal transplantation.
Curr Opin Urol. 2000 Mar;10(2):63-9.
Nagai Y, Yamashita H, Takamura T, Kobayashi KI.
Does acute hyperinsulinaemia change plasma adrenomedullin concentration in healthy men?
Diabet Med. 2000 Mar;17(3):249-50. No abstract available.
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Hinson JP, Kapas S, Smith DM.
Adrenomedullin, a multifunctional regulatory peptide.
Endocr Rev. 2000 Apr;21(2):138-67.
Chakravarty P, Suthar TP, Coppock HA, Nicholl CG, Bloom SR, Legon S, Smith DM.
CGRP and adrenomedullin binding correlates with transcript levels for Calcitonin Receptor-Like Receptor (CRLR) and Receptor Activity Modifying Proteins (RAMPs) in rat tissues.
Br J Pharmacol. 2000 May 1;130(1):189-195.
Ono Y, Okano I, Kojima M, Okada K, Kangawa K.
Decreased Gene Expression of Adrenomedullin Receptor in Mouse Lungs during Sepsis.
Biochem Biophys Res Commun. 2000 Apr 29;271(1):197-202.
Elkas J, Armstrong A, Pohl J, Cuttitta F, Martinez A, Gray K.
Modulation of endometrial steroid receptors and growth regulatory genes by tamoxifen(1).
Obstet Gynecol. 2000 May 1;95(5):697-703.
Frayon S, Cueille C, Gnidehou S, de Vernejoul MC, Garel JM.
Dexamethasone Increases RAMP1 and CRLR mRNA Expressions in Human Vascular Smooth Muscle Cells.
Biochem Biophys Res Commun. 2000 Apr 21;270(3):1063-1067.
Israel A, Diaz E.
Diuretic and natriuretic action of adrenomedullin administered intracerebroventricularly in conscious rats.
Regul Pept. 2000 May 10;89(1-3):13-18.
Shimosawa T, Kanozawa K, Nagasawa R, Mitarai T, Isoda K, Takahashi K, Ando K, Tozawa Y, Nagase M, Sasaki N, Fujita M, Takano K, Iiri T, Fujita T.
Adrenomedullin amidation enzyme activities in hypertensive patients.
Hypertens Res. 2000 Mar;23(2):167-71.
Aldecoa A, Gujer R, Fischer JA, Born W
Mammalian calcitonin receptor-like receptor/receptor activity modifying protein complexes define calcitonin gene-related peptide and adrenomedullin receptors in Drosophila Schneider 2 cells.
FEBS Lett. 2000 Apr 14;471(2-3):156-160.
Goto K, Fujii K, Onaka U, Abe I, Fujishima M.
Effects of adrenomedullin and PAMP on membrane potential and neurotransmission*.
Peptides. 2000 Feb 1;21(2):257-263.
Takahashi K, Yoshinoya A, Murakami O, Totsune K, Shibahara S.
Production and secretion of two vasoactive peptides, adrenomedullin and endothelin-1, by cultured human adrenocortical carcinoma cells.
Peptides. 2000 Feb 1;21(2):251-256.
Udono T, Totsune K, Takahashi K, Abe T, Sato M, Shibahara S, Tamai M.
Increased expression of adrenomedullin mRNA in the tissues of intraocular and orbital tumors.
Am J Ophthalmol. 2000 Apr 1;129(4):555-556.
Drake WM, Lowe SR, Mirtella A, Bartlett TJ, Clark AJ.
Desensitisation of calcitonin gene-related peptide responsiveness but not adrenomedullin responsiveness in vascular smooth muscle cells.
J Endocrinol. 2000 Apr;165(1):133-138.
Nagaya N, Nishikimi T, Yoshihara F, Horio T, Morimoto A, Kangawa K.
Cardiac adrenomedullin gene expression and peptide accumulation after acute myocardial infarction in rats.
Am J Physiol Regul Integr Comp Physiol. 2000 Apr;278(4):R1019-R1026.
Kamiya H, Okumura K, Sone T, Tsuboi H, Kondo J, Mukawa H, Matsui H, Toki Y, Ito T, Hayakawa T.
Plasma adrenomedullin levels in the coronary circulation in vasospastic angina pectoris.
Am J Cardiol. 2000 Mar 1;85(5):656-8, A10.
Wang H, Tomikawa M, Jones MK, Pai R, Sarfeh IJ, Tarnawski AS.
Sequential expression of adrenomedullin and its receptor during gastric ulcer healing in rats.
Dig Dis Sci. 2000 Mar;45(3):591-8.
Rossi F, Guerrini L, Pasimeni G, Markouizou A, Fabbrini A, Santiemma V.
Testicular peritubular myoid cells are a target for adrenomedullin.
Arch Androl. 2000 Mar-Apr;44(2):103-7.
Authors Champion HC. Bivalacqua TJ. Toyoda K. Heistad DD. Hyman AL. Kadowitz PJ. Title In vivo gene transfer of prepro-calcitonin gene-related peptide to the lung attenuates chronic hypoxia-induced pulmonary hypertension in the mouse Source Circulation 2000 Feb 29;101(8):923-30 Authors Cases A. Esforzado N. Lario S. Vera M. Lopez-Pedret J. Rivera-Fillat F. Jimenez W Title Increased plasma adrenomedullin levels in hemodialysis patients with sustained hypotension. Source Kidney International 2000 Feb;57(2):664-70 Authors Yoshihara F. Nishikimi T. Horio T. Yutani C. Nagaya N. Matsuo H. Ohe T. Kangawa K. Title Ventricular adrenomedullin concentration is a sensitive biochemical marker for volume and pressure overload in rats. Source American Journal of Physiology - Heart & Circulatory Physiology 2000 Feb;278(2):H633-42 Authors Nagaya N. Satoh T. Nishikimi T. Uematsu M. Furuichi S. Sakamaki F. Oya H. Kyotani S. Nakanishi N. Goto Y. Masuda Y. Miyatake K. Kangawa K. Title Hemodynamic, renal, and hormonal effects of adrenomedullin infusion in patients with congestive heart failure. Source Circulation. 101(5):498-503, 2000 Feb 8. Authors Oie E. Vinge LE. Yndestad A. Sandberg C. Grogaard HK. Attramadal H. Title Induction of a myocardial adrenomedullin signaling system during ischemic heart failure in rats. Source Circulation. 101(4):415-22, 2000 Feb 1. Authors Petrie MC. Hillier C. Morton JJ. McMurray JJ. Title Adrenomedullin selectively inhibits angiotensin II-induced aldosterone secretion in humans. Source Journal of Hypertension 2000 Jan;18(1):61-4 Authors Parameswaran N. Nambi P. Hall CS. Brooks DP. Spielman WS. Title Adrenomedullin decreases extracellular signal-regulated kinase activity through an increase in protein phosphatase-2A activity in mesangial cells. Source European Journal of Pharmacology 2000 Jan 28;388(2):133-8 Authors Takahashi K. Nakayama M. Totsune K. Murakami O. Sone M. Kitamuro T. Yoshinoya A. Shibahara S. Title Increased secretion of adrenomedullin from cultured human astrocytes by cytokines. Source J Neurochem. 74(1):99-103, 2000 Jan. Authors Martinez A. Kapas S. Miller MJ. Ward Y. Cuttitta F. Title Coexpression of receptors for adrenomedullin, calcitonin gene-related peptide, and amylin in pancreatic beta-cells. Source Endocrinology. 141(1):406-11, 2000 Jan. Authors Zumpe ET. Tilakaratne N. Fraser NJ. Christopoulos G. Foord SM. Sexton PM. Title Multiple ramp domains are required for generation of amylin receptor phenotype from the calcitonin receptor gene product. Source Biochem Biophys Res Commun. 267(1):368-72, 2000 Jan 7.